Tobacco and Cardiovascular Disease: A Summary of Evidence

Authors: Ambuj Roy, Ishita Rawal, Samer Jabbour, Dorairaj Prabhakaran


Tobacco kills nearly half of the people who use it, making it a serious global public health threat, and it is the single most preventable cause of cardiovascular disease. Research has demonstrated the myriad pathophysiological mechanisms by which tobacco harms the cardiovascular system, and evidence makes clear its adverse effects on cardiovascular morbidity and mortality, accounting for at least 10 percent of global cardiovascular deaths. Tobacco use also has definitive harmful effect on exposed nonsmokers. In response, the United Nations General Assembly agreed to target a 30 percent reduction in tobacco use from 2010 levels as a crucial step toward the goal of reducing premature mortality from no communicable diseases by 25 percent by 2025 (the 25x25 goal). The benefits of quitting tobacco kick in early, with substantial reduction in cardiovascular risk. The need is urgent for proven, cost-effective, individual-level interventions, with support from health providers and interventions agreed by governments in the Framework Convention on Tobacco Control



To submit comments or queries about this chapter, send an email to corresponding author, Dr. D. Prabhakaran, at

1.33 MB