Drug Resistant Infections

Authors: Molly Miller-Petrie, Suraj Pant, Ramanan Laxminarayan

The global rise in antibiotic resistance threatens to undo decades of progress in treating infectious diseases caused by bacterial pathogens (Laxminarayan and others 2006). Resistance to the drugs used to treat malaria, human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), and tuberculosis is also a serious concern, with multidrugresistant and extensively drug resistant tuberculosis now documented worldwide, particularly in China, India, and the Russian Federation (WHO 2014). These diseases and their treatment are covered in depth in other chapters in this volume. This chapter deals specifically with antibiotic resistance in humans and animals.