HIV/AIDS Co-morbidities: Impact on Cancer, Non-Communicable Disease, and Reproductive Health

Authors: Corey Casper, Heidi Crane, Manoj Menon, Deborah Money

Abstract:
People living with HIV face complications from associated health conditions including cancer, reproductive ill health, and the noncommunicable diseases of cardiovascular disease, diabetes, renal dysfunction, and liver damage. In terms of malignancies, Kaposi sarcoma is the most common HIV-associated, followed by cervical cancer, lymphoma, anal cancer, lung cancer, and hepatocellular carcinoma. For women, the HIV epidemic has had a substantial impact on their reproductive health, especially as a cause of infertility. Other sexually transmitted infections associated with HIV include human papillomavirus (HPV) and pelvic inflammatory disease. While ART increases longevity of HIV patients, it increases risk of cardiovascular disease and dyslipidemia; for people living with HIV in North America and Europe the prevalence of diabetes increases.