Sexually Transmitted Infections: Impact and Cost-Effectiveness of Prevention

Authors: Harrell W. Chesson, Philippe Mayaud, Sevgi O. Aral

Sexually transmitted infections (STIs) impose major health and economic burdens globally. More than 35 bacterial, viral, and parasitic pathogens have been identified as sexually transmissible. An estimated 498.9 million new cases of four of the curable STIs occurred among adults ages 15–49 years in 2008, an increase of 11.3 percent from the estimated 448.3 million new cases in 2005 (WHO 2012a). In 2008, these cases included 105.7 million new cases of chlamydia, 106.1 million new cases of gonorrhea, 10.6 million new cases of syphilis, and 276.4 million new cases of trichomoniasis (WHO 2012a).